It is X as of the Websters Dictionary. It only has 25. But in Second is Q.
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Five letter words that begin with the letter e:eagleearlyeartheaseleightelateelbowelectelopeeludeemailemberemceeemptyenactendowenjoyenterequiperaseethicevictevokeexact
3 letter words begin with n:nabnagnapnetnewnilnipnitnixnobnodnornotnownubnunnut
THere are 303 words that begin with the letter X.
Several four letter words begin with the letter q. However, there are no four letter words that begin with the letter q and end with the letter o.
Incompetent and ignorant are mean words. They begin with the letter i.