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If you don't want to waste time using other balls, yes, u should. But it is possible to nab him with another ball. Lueroi, a good YouTube video maker, caught Mewtwo with a GREAT BAll. He used his master ball on something else. If you don't want to waste your MAster ball, don't.

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13y ago

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Q: Should you use your masterball on Mewtwo?
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