Only if you have a code breaker and the master code for ruby plus the mew and mewtwo code
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the mew code for ruby is 71E09BD117FDFD02 and mewtwo is 30621E6F164FED85 these are the right once i think
Mew can't be catched in Pokemon heartgold, only mewtwo.
as i know, in Pokemon emerald, ruby and sphere
you can't Mew and Mewtwo are two completely different pokemon. Mewtwo is accually a clone of the original Mew. So... no, you can't evolve Mew into Mewtwo.
You cannot catch Mewtwo in Pokemon Crystal, but you can trade it from a Pokemon Red or Blue. Hope this helped :)