Either (1) when one player plays all their letters, and there are no more tiles remaining to draw OR (2) when no players can play any of the tiles in their rack.
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The game ends when all the letter tiles of a player (the first to finish) are exhausted/used/played on the scrabble board.
Since the value of a blank tile is zero, there are no points awarded for a blank tile at the end of the game.
When you use all your letters at the end of the game you get to add the letter score from the letters on your opponent's rack (not their entire game score).
0 i think
The objective of Scrabble is to have the highest number of points at the end of the game, when the extra letters run out, and one person doesn't have any letters in their 'hand.'