Assign a button or key to the "select" command in the controller configuration settings.
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The best emulator is NO$GBA
You open and play them in an emulator. The best GBA emulator is Visual Boy Advance. http://vba.ngemu.com/
No, you can't because it is a GBA Rom. You can play it on the computer using a emulator. A good GBA emulator is the VisualBoyAdvance.
I think that's impossible and also I already tried