While in the NDS main start up screen, push the settings button (bottom center) and then go to the yellow button on the far right. follow the directions and you touch screen should be calibrated.
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While this is right, I find that my screen wont get past the first four calibration movements. I think its realling annoying but I have learnt to live with it.
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It depends. If the touch screen works, but isn't clicking where you want it to, then you need to calibrate it. You can do this on the Settings. If the touchscreen is not responding at all, then sorry, you need a new Nintendo DS.
The lower screen is a touch sensitive screen.
When I calibrate mine, I am stuck in an endless loop of calibration.
buy a new one
Nintendo - Dual Screen