Yes, you can. You score the S plus points for all letters in new word. You do not count bonus squares already used.
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There are 5 S's in Words With Friends. (The prior answer noted that there were 5 S's also in Scrabble. This is incorrect. In Scrabble, there are only 4 S's; Words With Friends features an additional S in its letter distribution.)
Here are some: [feel free to add]hopelessnessassesssessionsscissorsendlessness
6-letter wordsvizsla7-letter wordsvizslas8-letter wordsbritzska9-letter wordsbritzskas4 words found.
4 Letter Scrabble Wordsdampdarkdrammarkpardparkpramramp3 Letter Scrabble Wordsamparkarmdakdamdapmadmapmarpadpamparradramrap2 Letter Scrabble Wordsadamarkamapa
salt,sail,wail,wilts,