There is only one mine but many people who teleport you to it there are 3 in F2P and 5 in total for members
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If you mean a talisman, a talisman is an item in RuneScape which, after completing the quest Rune Mysteries, allows you to create runes by having rune essence or pure essence in your inventory, mined from rune essence mines. Left click it to give you directions to the altar. Then, use the talisman on the altar, and click on the stone in the middle. Congratulations, you have made runes. Depending on which altar you went to, you will make runes of that kind.
The quest "Rune Mysteries" is a prerequisite to mine rune essence, and to make the actual runes.There is a rune essence mine. Go to Aubury (south of the eastern Varrock bank); he will teleport you if you did the quest.You can of course buy rune essence from the Grand Exchange - rune essence that was obtained and sold by other players.You also get small amounts of rune essence as drops from certain monsters.
F2P: Air rune Earth rune Fire rune Water rune Body rune Chaos rune Cosmic rune Death rune Law rune Mind rune Nature rune P2P: Dust rune Lava rune Mist rune Mud rune Smoke rune Steam rune Astral rune Blood rune Soul rune Extra: Rune Essence(F2P) Pure Essence(P2P) As you can see there is quite a few -Dd_rulez
You can't. If you're a member when you mine the essence it is pure essence but if you are just free-to-play then it just comes out as rune essence.
You need to get rune essence, an appropriate talisman, and have completed the quest " Rune mysteries". Then you need to go to the correct altar and use your talisman on the stone, then use your rune essence on the altar.