Coke goes flat because the carbonation used to make it fizzy is put into the soda under pressure. Once the cap is removed, it is no longer under pressure and the CO2 gas can escape. The bubbles you see are made of CO2 (Carbon Dioxide). Once the CO2 is gone it is flat.
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I have experimented with this subject quite a bit, and I have found through my results that if you slowly introduce a teaspoon of table sugar to an 8-12az. glass of cola, it fizzes and foams up immediately, though after the foam has fizzled away the soda tend to be flat (and a bit sweeter due to the introduction of the sugar)
The table sugar, interacts with the carbonated water,(which is a key ingredient in all soda). (Disclaimer: I would STRONGLY urge against this method for any and ALL individuals who suffer from ANY form of Diabetes. )
No more fizz. Soda gets its Carbonation from Carbon Dioxide gas passed through water in the processing plant. The evidence of the carbonation is the fizz, bubbles, and bite on the tongue that you feel when you drink it. However, Carbon Dioxide dissipates when exposed to air. No fizz in the glass = no carbonation in the drink.
The fastest way to make any carbonated beverage go flat is to heat it. The heat impedes the liquid's ability to hold the carbonation.
Leave the bottle or can open and let loads of air in, if possible leave it in the fridge so there isn't a risk of flies getting into it! :P