For perishable foods, the maximum temperature would be 40°F (4.4°C). But vacuum-packaged seafood should not be above 38°F (3.3°C) due to the possibility of the formation of the botulism toxin.
Normally, higher settings will have the refrigerator run more efficiently since it won't have to run as hard to maintain the temperature. But higher temperatures are not as safe nor do they keep foods as long as colder temperatures.
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A refrigerator should normally operate at a temperature of 38 degrees. It is important to keep your refrigerator at the right temperature in order to ensure that your food does not spoil.