Harry's father, James Potter, was one of Lupin's best friend. Harry reminds Lupin very much of James.
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Yes, Lupin and Tonk's asked Harry to be Theadore's godfather.
Harry is the Godfather of little Teddy Lupin. The son of Nymphadora Tonks and Remus Lupin.
Teddy Lupin
When Lupin was a little boy, his father had a fight with Fenrir Greyback, who said he would get revenge, and he did by biting Lupin.
Nymphadora Tonks Remus Lupin and Nymphodora Tonks get married in the Deathly Hollows. They also have a baby boy, Teddy Lupin, Godson of Harry Potter