Who were Warren Tay and Bernard Sachs?

Answer 1

They were the two people directly responsible for identifying Tay Sachs Disease or aka TSD. It was first identified by British ophthalmologist Warren Tay in 1881 and American physician Bernard Sachs in 1887, consequently receiving its name "Tay-Sachs". Tay concentrated on eye changes and described eye defects in an infant with a progressive neurological disease. This is also known as a "cherry-red spot" found in the macula in the back of the eye, it's a characteristic of this disorder. Sachs focused on clinical features, diagnostic signs and pathology, he presented his observations of a disease that was common among German immigrants of Jewish heritage. TSD is most common in Ashkenazi Jews, which are Jews descending from Central or Eastern Europe, and it's also found in some French Canadians. This disease is an autosomal recessive condition meaning that a carrier isn't affected by it but if two carriers cross then there is a 25% chance of a child being affected by it.