Actually it comes to a tie. Both Sean Hayes (who plays Jack) and Megan Mullally (who plays Karen) won an Emmy in 2000. Sean Hayes won "Outstanding Supporting Actor in a Comedy Series" and Megan Mullally won "Outstanding Supporting Actress in a Comedy Series".
Life Goes On
Yes the cast member was hakeem he died in 2003 from a car accident
debra messing
Grace Kelly
The cast of Nancy Grace Reacts to Casey Anthony Verdict - 2011 includes: Alex Fernie
Bill Murray
Bill Murray
Chevy Chase
Phil Hartman
Helen Hayes.
The only regular cast member of "e.r." to win an Emmy was Julianna Margulies, who received the 1994 award for Outstanding Supporting Actress in a Drama Series.
Gavin MacLeod
The cast of Carl Emmy and His Dogs - 1916 includes: Carl Emmy as Himself - Dog Trainer
The cast of Won in the First - 1914 includes: Grace Cunard
Robert Sean Leonard
Gilda Radner
It looks like the first time a female former cast member hosted SNL wasn't until the 13th of May 2006, the first time Julia Louis-Dreyfus hosted. She was also the first female former cast member to host a second time, on the 17th of March 2007.The first male former cast member to host SNL was Chevy Chase on the 18th of February 1978. He was also the first to host a second time, on the 9th of February 1980. (From the end of the 1st season in 1976 to the end of the 5th season in 1980, Chevy Chase was the ONLY former cast member. Bill Murray, the first cast member who was not part of the original cast, hosted twice in 1981.)