Brian's Song is a 1971 madeforTV movie, recalling the details of the life of Brian Piccolo (played by James Caan) a white football player stricken with terminal cancer, and his friendship with black Chicago Bears running back teammate and Pro Football Hall of Famer Gale Sayers (Billy Dee Williams), who helps him through the difficult struggle.
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Brian Krause
Brian Baumgartner
If you are talking about the movie "Matilda" it was Danny Devito.
Brian Doyle-Murray portrayed Mr. Shirley in the 1989 holiday comedy starring Chevy Chase.