If it is the commercial I am thinking of, the actress is Meredith Forlenza, based in New York.
I've provided a link to this Pearle Vision commercial to confirm we are speaking of the same person. It is possible there is a different Lenscrafters commercial. For that matter, both companies are owned by Luxottica, and her performance may also be aired as a Lenscrafters commercial.
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Lorri Hamm has: Played Maggie Siems in "Dead Flesh" in 2001. Played Cat in "Brushfires" in 2004. Played Thelma in "The Game" in 2004. Played Catelyn in "Twelve Ones" in 2005. Played Cat in "Smoke" in 2006. Played Meredith in "Maidenhead" in 2008.
Rhoda Gemignani has: Played Alice in "Mary Tyler Moore" in 1970. Played Miss Rossi in "The Bob Newhart Show" in 1972. Played Joan Rossi in "The Bob Newhart Show" in 1972. Played Katrina Patropolous in "Kojak" in 1973. Played Francine in "Police Woman" in 1974. Played Aunt Olga in "NBC Special Treat" in 1975. Played Emily Bates in "The Jeffersons" in 1975. Played Mrs. Gerber in "Doc" in 1975. Performed in "Panic in Echo Park" in 1977. Played Evelyn in "The Facts of Life" in 1979. Played Mary Grasso in "The Triangle Factory Fire Scandal" in 1979. Played Russian ticket taker in "Die Laughing" in 1980. Played Mrs. Drossos in "Nero Wolfe" in 1981. Played Mrs. Biomonte in "Hill Street Blues" in 1981. Played Mrs. Theodakis in "Farrell for the People" in 1982. Played Andrea Novino in "St. Elsewhere" in 1982. Played Madame Rosa in "Still the Beaver" in 1983. Played Mrs. Palovsky in "Hunter" in 1984. Played Dorothy in "Goldie and the Bears" in 1984. Played Real Estate Woman in "Ghost Busters" in 1984. Played Sylvie in "Concrete Beat" in 1984. Played Mama Zinetta in "Mike Hammer" in 1984. Played Angelina (segment "Grace Note") in "The Twilight Zone" in 1985. Played Emily in "Moonlighting" in 1985. Played Marie (Present Day) in "Wiseguy" in 1987. Played Carla Styles in "Jake and the Fatman" in 1987. Played Mama in "Blood Vows: The Story of a Mafia Wife" in 1987. Played Irene Cochran in "Full House" in 1987. Played Rusty Rolleri in "Paradise" in 1988. Played Woman With Elaine in "Seinfeld" in 1989. Played Radio Operator in "Three Fugitives" in 1989. Played Mama Torzini in "Baywatch" in 1989. Played Aunt Marion in "Babes" in 1990. Played TV Producer in "Rock Hudson" in 1990. Played Mrs. Kaminsky in "Brooklyn Bridge" in 1991. Played Rudy DeMattis in "Family Album" in 1993. Played Yelena in "Walker, Texas Ranger" in 1993. Played Mrs. Potter in "Friends" in 1994. Played Miss Jacobs in "Charlie Grace" in 1995. Played Gail in "Caroline in the City" in 1995. Played Mamma Mia in "The What a Cartoon Show" in 1995. Played Pearl Frischetti in "The Great Defender" in 1995. Played Mrs. Costello in "Life with Roger" in 1996. Played Laraine Verma in "The Closer" in 1998. Played Momma in "NetForce" in 1999. Played Pasquelina Marchegiano in "Rocky Marciano" in 1999. Played Housing Services Secretary in "Related" in 2005.