extreme cold was what I got.
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You may be thinking of Professor John I.Q. Nerdelbaum Frink, Jr., who is named after John Frink, a Simpsons writer.
Lola Frink died on November 15, 1952, in Chicago, Illinois, USA.
Homer Simpson is a cartoon character therefore he never lived therefore cannot die.However...In Season 25's Days of Future Future he did in fact die but Professor Frink cloned him and he and many other clones lived well into the future.Naturally though, the future based episodes have nothing to do with the already fluid continuity of The Simpsons.
(August 02nd 2015) In 26 Seasons, there has been 574 episodes so there are far too many directors to list, however, some are Wes Anderson, Mike B Anderson, Brad Bird, David Silverman, Rich Moore, Mark Kirkland & Dominic Polcino.