Itachi begins to go blind the moment he obtain the Mangekyo Sharingan. That's the the price to pay for using a powerful eye technique. It explained that the more you use it, the faster the process of getting blind will be.
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No, Itachi was never shown smoking.
actually, sasuke didn't kill itachi. when they fought itachi was hurt or sick, and he died. he never intended on killing sasuke. sasuke didn't know about itachi's past
I know for sure you're talking about the latest and last fight Itachi had with Sasuke. Itachi was already close to dying, he was so close to death and blindness that he could of died without any fight; because of the overuse of Mangekyo Sharingan.
Itachi Uchiha part of the Uchiha clan also a member of the akatsuki
Obito mentioned that Itachi had a lover which he killed during the massacre. Other then that nothing is known about Itachi's love life.