Alexis Arquette is an American male-to-female transgender actress, musician, and cabaret drag performer. Though Alexis was actually born Robert Arquette, as a male, she has had a sex change and is thus, homosexual. She is the sister of David Arquette and Patricia Arquette.
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No, Alexis is in a relationship wiht heather Harris
Nothing is known of her sexual orientation.
The Joker's sexual orientation is not written into his character.
Soko's sexual orientation is heterosexual/straight.
The fictional character of Yoshi is not depicted with sexual orientation.