Season 1 , episode 10 : "Hall Monster / Hypno Birthday to You" which aired November 1, 2002 .
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They are children throughout the series obviously, but in the future-centric episode, The Tomorrow Boys, they aremarried.
Yes , James Isaac "Jimmy" Neutron was voiced by Debi Derryberry .
He was born with a high IQ and was eager to learn. So he read a lot of books and he understood everything and so he learned a lot and that is what you call smart, I guess. ---------- In the episode "Clash of the Cousins," it was stated that there was a "genius gene" that ran in the Neutron family, and only him and Baby Eddie (his evil cousin) had it.
It was in the jimmy neutron movie
I'm sorry, but no. That is scientific impossible.