No, but her first husband, Humphrey Bogart, played the male lead in what's now considered one of the greatest movies of all time, and undoubtedly the role he's most remembered for. The female lead went to Ingrid Bergman.
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After her first husband Humphrey Bogart's death in 1957 due to terminal cancer, Bacall was distraught as the relationship had lasted from when she was 19 until her 30's, and she admitted she felt "lost" after Bogart's death.
She remarried in 1961 to actor Jason Robards and they divorced in 1969. She cited his Alcoholism as the result of the eventual collapse of their marriage. They had one child together; Sam Robards.
No, she did not.
Lauren Bacall married Humphrey Bogart May 21, 1945.
Katherine Hepburn, Spencer Tracy, Humphrey Bogart and Lauren Bacall were the original Rat Pack. Lauren Bacall coined the term. Frank Sinatra and Lauren Bacall dated after Bogart's death, which is how he came to be associated with the name with his group of friends.
In the film "To Have And Have Not" (1944) directed by Howard Hawks, starring Humphrey Bogart and Lauren Bacall (in her screen debut); Lauren Bacall's character "Slim", says it to Humphrey Bogart's character "Steve" (Harry Morgan).
Lauren Bacall*