Yes. Deion is the Father of Emmanuel. As you can tell by the ressemblance in the nose.
Bo Jackson & Dion Sanders
No. Emmanuel Sanders and Deion Sanders are not related by blood.
Atlanta Falcons and Baltimore Ravens
Deion Sanders was #21 throughout his NFL career until he unretired to join the Ravens, when he had #37.
Dion Sanders. "Primetime"
no they are not related they just have the same last name like bob sanders.