Three.
1. At the the beginning of the series when he was hit by a car trying to save a little boy.
2. When he used up all of his spirit energy, he was forced to use his life energy to fire one last shotgun to defeat suzaku and save keiko.
3. Knowing he could not defeat sensui, he let himself be killed to unlock kuwabara, hiei, and kurama's untapped power by having them experience the loss of a close friend.
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3 times
2 times. Future Trunks got killed by cell and kid Trunks got killed by buu
Togoro killed Genkai because, when they were younger, they were in love. They, along with his brother Elder Togoro, entered the Dark Tournament and eventually won it. As his wish, Togoro asked to be turned into the "highest class of demon" in order to punish himself for what he thought was his fault in letting his students die. Genkai didn't agree with his decision or his self-blame, and instead asked to be left alone by the tournament committee. This angered Togoro, because he couldn't understand why she would allow herself to die when given the chance to live forever. Togoro was never able to understand why Genkai didn't choose to become a demon, and developed a lot of anger towards her. When Togoro killed Genkai he looked at it as her own fault, since she could have chosen to be like him. He never realized that the reason she left him was to try and save him from his own guilt and self-loathing, although Yusuke is able to see it almost immediately.
The orphan girl stabs him with a knife a couple times. :)
Cole comes into charmed at the beginning of season and then he dies many times but always comes back. He die for real in season 5. he does come back for one or two eps but that's it