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No, Bow Wow and Lil Mama are not brother and sister. They are both artists in the hip-hop industry, but they are not related. Bow Wow, whose real name is Shad Moss, is a rapper and actor, while Lil Mama, whose real name is Niatia Jessica Kirkland, is a rapper and singer. They have collaborated in the past but share no familial ties.
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lil wayne is lil mama sister
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