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Larry The Cable Guy as Mater

Owen Wilson as Lightning McQueen

Michael Caine as Finn McMissile

Emily Mortimer as Holley Shiftwell

Vanessa Redgrave as The Queen and Mama Topolino

David Hobbs as David Hobbscap

Lewis Hamilton as Lewis Hamilton

Jeff Gordon as Jeff Gorvette

Darrell Waltrip as Darrell Cartrip

Thomas Kretschmann as Professor Z

Michel Michelis as Tomber

Bruce Campbell as Rod "Torque" Redline

Eddie Izzard as Sir Miles Axlerod

John Tuturro as Francesco Bernoulli

Franco Nero as Uncle Topolino

Peter Jacobson as Acer

Joe Mantegna as Grem

Jason Isaacs as Siddeley and Leland Turbo

Tony Shalhoub as Luigi

Guido Quaroni as Guido

Paul Dooley as Sarge

Llyod Sherr as Fillmore and Combat Ship

John Ratzenberger as Mack

Bonnie Hunt as Sally Carrera

Michael Wallis as Sheriff

Katherine Helmond as Lizzie

Jennifer Lewis as Flo

Cheech marin as Ramone

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