Yes youll get totally blitzed start wit 4 or 5 milligrams!! And then go play yugioh with your friends, it's the funnest thing in the world
Two of the most common medications used to treat secretions are both antimuscarinic - scopolamine and glycopyrrolate.
Anticholinergic drugs are substances used to help reduce and block the effects of acetylcholine. They are mainly used for the treatment of stomach cramps, motion sickness and ulcers. Some anticholinergic drugs include: Ipatropium Bromide Oxitropium Bromide Tiotropium Glycopyrrolate
Robinul (Glycopyrrolate) is a medication that my son (age 4) uses to control drooling. He has mild cerebral palsy and the medication has helped greatly. When they are little, drooling is not so bad but as they grow it really inhibits social interaction. It is my understanding that the seasickness patch is also used by some people.
Anticholinergic drugs are substances used to help reduce and block the effects of acetylcholine. They are mainly used for the treatment of stomach cramps, motion sickness and ulcers. Some anticholinergic drugs include: Ipatropium Bromide Oxitropium Bromide Tiotropium Glycopyrrolate
Xylazine, an alpha-2 agonist, may be reversed using yohimbine. However, it is not reversed every time it is used. Xylazine (also known by the trade name Rompun) frequently wears off quickly enough that reversal is not needed. This would particularly be true if used as an anesthesia pre-medication prior to propofol or thiopental induction. If xylazine is used as the sole anesthestic induction agent, the duration of the procedure would dictate whether or not yohimbine would be necessary. Yohimbine can also be used to reverse xylazine if a patient's heart rate or blood pressure goes down while under anesthesia and a faster recovery is desired. Combining xylazine with an anticholinergic like glycopyrrolate would help prevent the bradycardia associated with xylazine.
Antispasmodic medications are in the class of drugs called anticholinergics. These are also referred to as MRA (Muscarinic Receptor Antagonists). There is not a specific drug always used, there are many choices.According to a recent publication, Clinical Anesthesia,by Barash, Cullen, Stoelting, Cahalan and Stock, current anesthesia practices do not routinely use atropine for this, as was common in the past:"The advent of newer inhalation agents has almost completely dispelled the routine use of anticholinergic drugs for preoperative medication...Specific indications for an anticholinergic before surgery are (1) antisialagogue effect [drying of the upper airway secretions] and (2) sedation and amnesia...Uses that are less firmly established and not universally agreed on include the preoperative prescription of anticholinergics for their vagolytic action or in an attempt to decrease gastric acid secretion... Scopolamine is a more potent drying agent than atropine...Glycopyrrolate is a more potent and longer acting antisialagogue than atropine...When sedation and amnesia are desired...scopolamine is frequently the anticholenergic chosen, especially in combination with morphine."
The following list may not be complete. Please check with your health care provider or pharmacist for all drug interations..glycopyrrolate (Robinul);lithium (Eskalith, LithoBid);hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic);mepenzolate (Cantil);metformin (Glucophage, Actoplus Met, Avandamet, Fortamet, Janumet, PrandiMet, Riomet);atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);glaucoma medications such as acetazolamide (Diamox) or methazolamide (Neptazane);irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro-Banthine); orother seizure medications such as carbamazepine (Carbatrol, Tegretol), lamotrigine (Lamictal), phenytoin (Dilantin), valproic acid (Depakote, Depakene), or zonisamide (Zonegran).Also avoid Ketogenic diets (such as Atkins, etc.) that have you increase your protein intake and limit the carbs you eat as this can cause kidney stones.Drink plenty of fluids while taking this drug as it can cause you to become dehydrated easilly.
The medical term is "palmar hyperhidrosis". It can be a physical condition or it can be caused by anxiety.There are a number of ways to "treat" sweaty hands. TOPICAL APPLICATIONS:1. Antiperspirants. The Aluminium Chloride (AlCl) in these blocks sweat from leaving your body eg, Driclor, Drysol.2. Alternate Topical Applications such as hydrosal (A new first-line topical gel treatment for excessive sweating. Developed by dermatologists, the gel contains salicylic acid which, as well as having antiperspirant properties of its own, is meant to enhance the penetration of aluminum chloride. The absence of ethanol also reduces irritaion), secure wipes (These are like a tissue or pad which are wiped across the area. The glycopyrrolate prevents synaptic transmission as the "messenger" acetylcholine is inhibited from stimulating receptors on the sweat glands.), etc. ORAL MEDICATION: In general these may be effective but they have been know to have MANY side effects like memory loss, etc.IONTOPHORESIS: This involves placeing the hands and/or feet into shallow trays filled with water, while a small electrical current is passed into metal plates and the water. After 5-10 initial treatments dryness can last up to 3 weeks in applied areas. To use this method you can either buy a Iontophoresis machine (expensive) or I have found a very useful guide to making your own at http://www.sweatinghands.net.BOTOX: The responses have been as long as 1 year, but in most cases the anhidrosis effect begins to weaken in 4 months. It is usually very expensive unless covered by insurance. It may be used on the hands and feet but with less effect than the armpits. Injections in the hands and feet have been reported to be painful. Slight numbness of the thumb has been reported (caused by injection or diffusion of molecules into thenar muscle).SURGERY: Endoscopic Thoracic Sympathectomy. The last resort. This is a procedure that generates conflicting opinions due to a very diverse range of possible side effects. In general terms ETS does not offer a true cure for hyperhidrosis, but usually moves sweat from one area to another - referred to as reflex sweating.In general most of my patients have found Iontophoresis to be the best method but it is really up for you to decide which works best for you. If you decide to go for Iontophoresis please look at : http://www.sweatinghands.net
DefinitionHyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest.Alternative NamesSweating - excessive; Perspiration - excessive; DiaphoresisCauses, incidence, and risk factorsSweating helps the body stay cool. In most cases, it is perfectly natural. People sweat more in warm temperatures, when they exercise, or in response to situations that make them nervous, angry, embarrassed, or afraid.However, excessive sweating occurs without such triggers. Those with hyperhidrosis appear to have overactive sweat glands. The uncontrollable sweating can lead to significant discomfort, both physical and emotional.When excessive sweating affects the hands, feet, and armpits, it's called primary or focal hyperhidrosis. Primary hyperhidrosis affects 2 - 3% of the population, yet less than 40% of patients with this condition seek medical advice. In the majority of primary hyperhidrosis cases, no cause can be found. It seems to run in families.If the sweating occurs as a result of another medical condition, it is called secondary hyperhidrosis. The sweating may be all over the body, or it may be in one area. Conditions that cause second hyperhidrosis include:AcromegalyAnxiety conditionsCancerCarcinoid syndromeCertain medications and substances of abuseGlucose control disordersHeart diseaseHyperthyroidismLung diseaseMenopauseParkinson's diseasePheochromocytomaSpinal cord injuryStrokeTuberculosis or other infectionsSymptomsThe primary symptom of hyperhidrosis is wetness.Signs and testsVisible signs of sweating may be noted during a doctor's visit. A number of tests may also be used to diagnose excessive sweating. Tests include:Tests include:Starch-iodine test. An iodine solution is applied to the sweaty area. After it dries, starch is sprinkled on the area. The starch-iodine combination turns a dark blue color wherever there is excess sweat.Paper test. Special paper is placed on the affected area to absorb the sweat, and then weighed. The heavier it weights, the more sweat has accumulated.You may be also be asked details about your sweating, such as:Location Does it occur your face, palms, or armpits, or all over the body?Time pattern Does it occur at night?Did it begin suddenly?Triggers Does the sweating occur when you are reminded of something that upset you (such as traumatic event)?What other symptoms do you have, for example: Weight lossPounding heartbeatCold or clammy handsFeverLack of appetiteTreatmentTreatments may include:Antiperspirants. Excessive sweating may be controlled with strong anti-perspirants, which plug the sweat ducts. Products containing 10% to 15% aluminum chloride hexahydrate are the first line of treatment for underarm sweating. Some patients may be be prescribed a product containing a higher dose of aluminum chloride, which is applied nightly onto the affected areas. Antiperspirants can cause skin irritation, and large doses of aluminum chloride can damage clothing. Note: Deodorants do not prevent sweating, but are helpful in reducing body odor.Medication. Anticholinergics drugs, such as glycopyrrolate (Robinul, Robinul-Forte), help to prevent the stimulation of sweat glands. Although effective for some patients, these drugs have not been studied as well as other treatments. Side effects include dry mouth, dizziness, and problems with urination. Beta-blockers or benzodiazepines may help reduce stress-related sweating.Iontophoresis. This FDA-approved procedure uses electricity to temporarily turn off the sweat gland. It is most effective for sweating of the hands and feet. The hands or feet are placed into water, and then a gentle current of electricity is passed through it. The electricity is gradually increased until the patient feels a light tingling sensation. The therapy lasts about 10-20 minutes and requires several sessions. Side effects include skin cracking and blisters, although rare.Botox. Botulinum toxin type A (Botox) is FDA approved for the treatment of severe underarm sweating, a condition called primary axillary hyperhidrosis. Small doses of purified botulinum toxin injected into the underarm temporarily block the nerves that stimulate sweating. Side effects include injection-site pain and flu-like symptoms. If you are considering Botox for other areas of excessive sweating talk to your doctor in detail. Botox used for sweating of the palms can cause mild, but temporary weakness and intense pain.Endoscopic thoracic sympathectomy (ETS). In severe cases, a minimally-invasive surgical procedure called sympathectomy may be recommended when other treatments fail. The procedure turns off the signal that tells the body to sweat excessively. It is usually done on patients whose palms sweat much more heavily than normal. It may also be used to treat extreme sweating of the face. ETS does not work as well for those with excessive armpit sweating. See: ETS surgerySupport GroupsInternational Hyperhidrosis Society,www.sweathelp.orgExpectations (prognosis)Aluminum Chloride: Initially a patient may need to use it three to seven times a week. After sweating becomes normal, the person may need to use it only once every one to three weeks. If skin irritation is a problem, a doctor may temporarily prescribe a steroid-based cream.Botox: Swelling goes away in a few weeks. The effect of a single injection can last up to a few months. Some patients need additional injections.Iontophoresis: Sweating may be reduced after six to 10 sessions. After that, the person may need treatment once every one to four weeks.ComplicationsSome of the causes of hyperhidrosis can be serious. Always consult a doctor if you have excessive sweating.Calling your health care providerCall your health care provider if you have:Prolonged, excessive, and unexplained sweatingSweating with or followed by chest pain or pressureSweating with weight lossSweating that most often occurs during sleepSweating with fever, weight loss, chest pain, shortness of breath, or a rapid, pounding heartbeat - these symptoms may be a sign of an underlying disease, such as hyperthyroidismReferencesBoley TM, Belangee KN, Markwell S, Hazelrigg SR. The Effect of Thoracoscopic Sympathectomy on Quality of Life and Symptom Management of Hyperhidrosis. Journal of the American College of Surgeons. March 2007;204(3).Reisfeld R, Berliner KI. Evidence-based review of the nonsurgical management of hyperhidrosis. Thorac Surg Clin. 2008 May;18(2):157-66. Review.Hornberger J, Grimes K et al. Recognition, diagnosis and treatment of primary focal hyperhidrosis. J Am Acad Dermatol2004; 51: 274-86Lowe NJ, Glaser DA, Eadie N, et al. J Am Acad Dermatol. 2007 Apr;56(4):604-11. Epub 2007 Feb 15.Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety.Solish N, Benohanian A, Kowalski JW. Prospective open-label study of botulinum toxin type A in patients with axillary hyperhidrosis: effects on functional impairment and quality of life. Dermatol Surg. 2005 Apr;31(4):405-13.
= Reglan = Generic Name: metoclopramide (meh toe KLOE pra mide)Brand Names: Reglan Reglan increases muscle contractions in upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Reglan is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms. Reglan is also used to treat slow gastric emptying in people with diabetes (also called diabetic gastroparesis), which can cause nausea,You should not take Reglan if you are allergic to metoclopramide, or if you have bleeding or blockage in your stomach or intestines, epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma). Before taking Reglan, tell your doctor if you have kidney or liver disease, congestive heart failure, diabetes, or a history of depression. Avoid drinking alcohol. It can increase some of the side effects of Reglan. There are many other medicines that can interact with Reglan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. Stop using Reglan and call your doctor at once if you have tremors or uncontrolled muscle movements, fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing, depressed mood, thoughts of suicide or hurting yourself, hallucinations, anxiety, agitation, seizure, or jaundice (yellowing of your skin or eyes). After you stop taking Reglan, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.You should not take Reglan if you are allergic to metoclopramide, or if you have: * bleeding or blockage in your stomach or intestines; * a perforation (hole) in your stomach or intestines; * epilepsy or other seizure disorder; or * an adrenal gland tumor (pheochromocytoma). Before taking Reglan, tell your doctor if you have * kidney disease; * liver disease (especially cirrhosis); * congestive heart failure; * diabetes (your insulin dose may need adjusting); or * a history of depression. If you have any of these conditions, you may need a dose adjustment or special tests to safely take Reglan. FDA pregnancy category B. Reglan is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Reglan can pass into breast milk and may harm a nursing baby. Do not use Reglan without telling your doctor if you are breast-feeding a baby.Take Reglanexactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Take this medicine with a full glass of water. Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. The oral concentrate form of Reglan must be mixed with another liquid, such as water, fruit juice, soda, or a soft food like applesauce or pudding. Carefully follow mixing directions to make sure you get the correct dose. Reglan is usually taken before meals and at bedtime. Your doctor may want you to take the medication as needed only with meals that usually cause heartburn. Follow your doctor's instructions. Store Reglan at room temperature away from moisture and heat. After you stop taking Reglan, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose. Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include drowsiness, confusion, tremors or uncontrolled muscle movements in face or neck, or seizure (convulsions). Narcotic pain medicine, sleeping pills, and medicine for anxiety can add to sleepiness caused by Reglan. Tell your doctor if you regularly use any of these other medicines. Avoid drinking alcohol. It can increase some of the side effects of Reglan. Metoclopramide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Reglan and call your doctor at once if you have any of these serious side effects: * tremors, or restless muscle movements in your eyes, tongue, jaw, or neck; * mask-like appearance of the face; * fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing; * depressed mood, thoughts of suicide or hurting yourself; * hallucinations, anxiety, agitation, jittery feeling, trouble staying still; * swelling, fluid retention; * jaundice (yellowing of your skin or eyes); or * seizure (convulsions). Less serious Reglanside effects may include: * feeling restless, drowsy, tired, or dizzy; * headache, sleep problems (insomnia); * nausea, diarrhea; * breast tenderness or swelling; * changes in your menstrual periods; or * urinating more than usual. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. Before taking Reglan, tell your doctor if you are taking any of the following medicines: * acetaminophen (Tylenol); * cyclosporine (Gengraf, Neoral, Sandimmune); * digoxin (digitalis, Lanoxin); * glycopyrrolate (Robinul); * levodopa (Larodopa, Atamet, Parcopa, Sinemet); * mepenzolate (Cantil); * tetracycline (Brodspec, Panmycin, Robitet, Sumycin, Tetracap, and others); * atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop); * bladder or urinary medications such as darifenacin (Enablex), tolterodine (Detrol), or solifenacin (Vesicare); * bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva); * irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), or propantheline (Pro-Banthine); or * an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate). This list is not complete and there may be other drugs that can interact with Reglan. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor. * Your pharmacist can provide more information about Reglan. * Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Reglan only for the indication prescribed. * Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.