0
That will vary greatly among different engine designs. Some V12's displace over 24 Liters others are small as 4 Liters (relatively small haha).
If you are changing your coolant then make sure the bottom radiator hose is attached and fill the engine block with a 50/50 mix of antifreeze and water through the thermostat housing (thermostat removed of course) reinstall the thermostat, connect the upper radiator hose and fill the radiator with the 50/50 mix. Close the radiator cap and run the engine for 5 mins, shut her down and refill the radiator. Job done!
-CJP
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