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Q: Chevy s-10 truck one cylinder misfire?
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What is random cylinder misfire?

It means that more than one cylinder has a misfire history. PO301 would be cylinder number 1 misfire. PO302 would be number 3 cylinder misfire.


Which is the 1 cylinder on a Chevy S-10?

If you have a 4 cylinder engine, the number one cylinder is the one closest to the front of the truck. If you have a 6 cylinder, it the on the driver side closest to the front of the truck


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Do fuel injectors involve misfire?

I'm not a mechanic / technician but I BELIEVE if the fuel injector is restricted so that the proper air - fuel mixture is not getting to an engine cylinder , that an engine cylinder misfire can occur ( that is only one of the causes of an engine cylinder misfire )


Can a misfire make a truck not start?

You have not given enough information to even begin to answer this question. If the truck won't start, What makes you think that it has a misfire? A misfire is typically one or more cylinders not firing when the truck is running. If you indeed have a dead cylinder, that alone will not keep the engine from starting , unless you have catastrophic failure,(Something broken inside the given cylinder). However if you are not getting any fire then the truck will not start. Also if the truck has recently run & it ran rough, (As in mis-firing), then it may need a tune-up , (Or something more involved), & if that condition is bad enough; then YES, it could keep the engine from starting.


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While an incorrect fuel/air ratio can cause a misfire, it's not likely to cause only one cylinder to misfire unless you have tuned port injection. The more likely cause is the ignition system... Distributor cap, rotor, plug wires, or spark plugs.


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A misfire is when one of the cylinders is accelerating without actually doing anything, it's just a dead-cylinder. In order to fix this you need to tighten the cylinder or adjust the engine connector.