The Mona Lisa is Leonard da Vincis most famous paintings.
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The most famous paintings Leonardo da vincis were : The Mona Lisa and The Last Supper
CAROULSEL
There are only 15 surviving paintings that are universally accepted to have been by Da Vinci; this is due to a combination of his desire to use new techniques - which occasionally caused disasters!) and his procrastination. However, his two most famous paintings - and arguably the two most famous paintings in the world - are the Mona Lisa and the Last Supper.
Technically his paintings are done quite traditionally in oil paint on wood panel.
Georgia O'Keeffe is most famous for her paintings of flowers. Her most famous paintings show the flowers in extreme close-up view.