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Rheumatoid factor (RF or RhF) antibody directed against an organism's own tissues) most relevant in rheumatoid-Arthritis. It is an antibody against the Fc portion of immunoglobulin-g-1, which is itself an antibody. RF and IgG join to form immune-complex-1 which contribute to the disease process. About 80% of people with rheumatoid arthritis have detectable rheumatoid factor. Those who do not are said to be "seronegative".
Rheumatoid factor can also be a cryoglobulinemia-1 (antibody that precipitates on cooling of a blood sample); it can be either type 2 (monoclonal IgM to polyclonal IgG) or 3 (polyclonal IgM to polyclonal IgG)
RF is often evaluated in patients suspected of having any form of arthritis even though positive results can be due to other causes, and negative results do not rule out disease. But, in combination with signs and symptom, it can play a role in both diagnosis and disease prognosis. It is part of the usual disease criteria of rheumatoid arthritis.
The presence of rheumatoid factor in serum can also indicate the occurrence of suspected autoimmune activity unrelated to rheumatoid arthritis, such as that associated with tissue or organ rejection. In such instances, RF may serve as one of serology markers for autoimmunity. (source wikipedia)
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Is a Rheumatoid Factor of 14 high enough to indicate RA?
It is possible to have RA without any Rheumatoid factor. This is known as seronegative RA. However if you are suspected of having RA then any RF (rheumatoid factor) helps complete the diagnosis towards the possibility of RA.
What are synonyms of seropositive arthritis?
Seropositive Rheumatoid arthritis is RA in a person that has rheumatoid factor in the blood. As opposed to seronegative RA where there is no RF.Rheumatoid arthritis is an autoimmune disease that exhibits itself in a certain way when it is suspected that one has RA ones blood is tested for Rheumatoid factor (a particular antibody) if it is found to be elevated then one is said to have seropositive RA.
What substance is found in the blood of patients with rheumatoid arthritis?
In about 70% of RA patients Rheumatoid factor is present.
Can you have rheumatoid arthritis with a rheumatoid factor 6.9?
Yes you can have RA with an Rf of 20. When a doctor sees the symptoms of RA they automatically check for RF because it is a good indicator that that is the problem when taking the symptoms into account , However you don't need any RF at all to be suffering from RA. When this happens it is described as "seronegative rheumatoid arthritis".An RF of more than 23 units and a titer over than 1:80 can indicate rheumatoid arthritis but may also occur in other conditions.A negative test result for rheumatoid factor does notnecesarily exclude the diagnosis of rheumatoid arthritis.
Can you have rheumatoid arthritis with a factor 7.7?
Yes You can have Rheumatoid arthritis with no RF at all. In that case it is referred to as seronegative RA,
