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Leflunomide, a DMARD, (disease modifying anti rheumatoid drug), will take about 3 to 6 weeks to lose its efficiency, that is decrease below its active blood level. You will continue to have it in your system for several more months the blood level will decrease slowly. If you need to get rid of the drug immediately, so you can start another drug that may affect your liver, your dr can give you activated charcoal or cholesteramine orally to absorb the drug. Contact the manufacturer for the details.

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Q: What happens when you stop taking the drug leflunomide cold turkey?
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