Oral glucosamine is commonly used for the treatment of osteoarthritis. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat Arthritis. Its use as a therapy for osteoarthritis appears safe, but there is conflicting evidence as to its effectiveness. A randomized, double-blind, placebo-controlled trial found glucosamine sulfate is no better than placebo in reducing the symptoms or progression of hip osteoarthritis.
There are two main types of glucosamine, Glucosamine Sulfate and Glucosamine hydrochloride. In a placebo controlled trials of Knee pain the Glucosamine Hydrochloride failed to show superority over placebo (GAIT) but a similar trial of the Glucoasmine Sulfate showed superiority over placebo and paracetamol in the control of pain.
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It is claimed that glucosamine aids the body in repairing damaged cartilage. However recent studies are finding that it makes no difference.
I have only heard that Shellfish are rich in glucosamine. One article I read stated that glucosamine is made from shellfish.
Synergistic glucosamine is a fancy way to say glucosamine sulfate potassium. Some supplements use this fancy name to make themselves look different than other products with the same ingredients.
Glucosamine chondroitin MSM is a very popular supplement, and is especially used by elderly individuals. Glucosamine chondroitin MSM is best used for joint health and to ease the pain of arthritis.
It appears that it is safe enough however there is no real evidence that it does anything for Arthritis
Glucosamine is one of the factors that make up cartilage. According to its manufacturers it is helpful in restoring damaged cartilage, and reduces arthritic pain. It is one of the most popular arthritis treatments sold over the counter without prescription.