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Oral glucosamine is commonly used for the treatment of osteoarthritis. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat Arthritis. Its use as a therapy for osteoarthritis appears safe, but there is conflicting evidence as to its effectiveness. A randomized, double-blind, placebo-controlled trial found glucosamine sulfate is no better than placebo in reducing the symptoms or progression of hip osteoarthritis.

There are two main types of glucosamine, Glucosamine Sulfate and Glucosamine hydrochloride. In a placebo controlled trials of Knee pain the Glucosamine Hydrochloride failed to show superority over placebo (GAIT) but a similar trial of the Glucoasmine Sulfate showed superiority over placebo and paracetamol in the control of pain.

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12y ago

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It is claimed that glucosamine aids the body in repairing damaged cartilage. However recent studies are finding that it makes no difference.

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15y ago
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