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He introduced the idea of scientific observation. (APEX) ^.^
Renaissance architecture (14th and 15th centuries), Baroque architecture (16 & 17th centuries) and Neoclassical architecture (18th and 19th centuries) were modeled on Roman architecture.
In a broad sense the Renaissance didn't end, it spread across western Europe and fed into a succession of artistic and intellectual phenomena. But central & northern Italy's loss of cultural leadership after the 15th century doubtless owes much to the upheavals and economic downturn following the French invasion of 1494 and the subsequent 65 years of intermittent Valois-Habsburg war, as well as to the shift of economic, cultural & political primacy to north-western Europe following the discovery of the Americas, the Reformation and the rise of national states.
During the renaissance it would have to be Firenze (Florence). The wealthy Medici family of merchants were great patrons of the arts sponsoring some of the greatest figures in western art such as Michelangelo, Da Vinci and Raphael.
They are best at Western then Classical