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Old or damaged RBCs are removed from the circulation by macrophages in the spleen and liver, and the hemoglobin they contain is broken down into heme and globin. The globin protein may be recycled, or broken down further to its constituent amino acids, which may be recycled or metabolized. The heme contains precious iron that is conserved and reused in the synthesis of new hemoglobin molecules.

During its metabolism, heme is converted to bilirubin, a yellow pigment that can discolor the skin and sclera of the eye if it accumulates in the blood, a condition known as jaundice. Instead, the plasma protein albumin binds to bilirubin and carries it to the liver, where it is secreted in bile and also contributes to the color of feces.

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Q: When hemoglobin is recycled what happens to the heme group?
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What part of the hemoglobin molecule is recycled to form bile?

A portion of the heme group


After hemoglobin is broken down into heme and globin what ultimately happens to the heme?

Heme is decomposed into iron and biliverdin


What ion is an essential factor in hemoglobin?

Hemoglobin contains a heme group with an Iron ion attached to it. This iron is what binds to O2.


Is heme and hemoglobin the same?

Heme + globin is Hemoglobin.


What is the iron-containing portion of the hemoglobin molecule called?

The iron containing part of hemoglobin is the 'heme' molecule.


In order for oxygen to be carried on the red blood cell the iron must be in the?

The name hemoglobin is derived from the words heme and globin, reflecting the fact that each subunit of hemoglobin is a globular protein with an embedded heme or iron group.


Is the mineral that combines with a protein to from hemoglobin?

There are four atoms of iron in a molecule of hemoglobin. Each iron atom is attached to a porphyrin, forming a heme group. Each heme group is attached to a polypeptide chain. There are two alpha and two beta polypeptides. So a hemoglobin molecule has four heme groups, and four polypeptides.


Which organ breaks down red blood cell?

The spleen breaks down old red blood cells. The contained hemoglobin is released, which is further broken to globin, a protein and heme, a porphyrin.The heme is converted to bilirubin, which moves from the spleen to the liver attached to albumin. (Both feces and urine get their color from the products of the breakdown of the heme.) The iron recycled from the breakdown of the heme group is stored in the liver.


What mineral is need for synthesis of hemoglobin?

Iron plays a critical role in the formation of hemoglobin.


What component in the plasma of red blood cells carries oxygen molecules to the somatic Cells?

The heme group of hemoglobin.


What are the uses of heme?

Heme is a ferrous ion prosthetic group (Fe2+) present in metalloproteins or specifically Hemoproteins such as Hemoglobin, porphyrin. heme is also found in proteins such as myoglobin, catalase, cytochromes. In these proteins Heme either participates in the catalysis or act as a stabilizer of active site amino acid.


What is the Organometallic iron compound found in hemoglobin?

Heme prosthetic group or Fe-protoporphyrin ix. A heme is madeup of protoporhyrin (ix) (organic compound) and Fe+2 (metal) hence organometallic.