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B-12 refers to a group of cobalt-containing vitamer compounds known as cobalamins: these include cyanocobalamin (an artifact formed as a result of the use of cyanide in the purification procedures), hydroxocobalamin (another medicinal form), and finally, the two naturally occurring cofactor forms of B-12: 5-deoxyadenosylcobalamin (adenosylcobalamin-AdoB-12), the cofactor of Methylmalonyl Coenzyme A mutase (MUT), and methylcobalamin (MeB-12), the cofactor of 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR).

The term B-12 may be properly used to refer to cyanocobalamin, the principal B-12 form used for foods and in nutritional supplements.[1]

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15y ago
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13y ago

B12 is cobalamin, the most common form is cyanocobalamin but although this can be absorbed in the intestines it cannot be used by the body until it is converted to methylcobalamin (a slow process and much of the cyanocobalamin is excreted before it could be converted). Sublingual methylcobalamin tablets are needed to get the usable form directly. Do not swallow methylcobalamin tablets as stomach acid will destroy this form of B12, they must be held under the tongue to dissolve and absorb through the mucus membrane of the mouth into the bloodstream.

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10y ago

cobalamin

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Q: What is the scientific name for vitamin B12?
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Explain the relation between vitamin b12 and pernicious anemia?

first of all its called vitamin b12 deficiency anemia. Pernicious anemia and vitamin B12 deficiency anemia are the same thing. Pernicious anemia is caused by a lack of vitamin B12. You're not able to absorb the vitamin B12 due to the absence of intrinsinc factor.


Can b12 vitamin increase the size of your neck?

No its not true. There is no such side effects of vit b12 vitamin.


Can a Vitamin B12 deficiency be connected to something serious like leukemia?

No, but a vitamin b12 deficiency cause megaloblastic anaemia


Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?

Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.


Why is vitamin B12 required?

Vitamin B12 is required for the biochemical reaction that converts homocysteine to methionine, one of the essential amino acids required to synthesize proteins.