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Onee-san and nee-san both mean older sister but onee-san is more formal than just nee-san.
You can also say onee-sama or nee-sama. Onee-sama is the most formal of them all nee-sama is less formal then onee-sama but more so than nee-san. Nee-chan is said too, it is the least formal of them all. The same rules go for older brother (nii-san).
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