What is the difference between endotoxin and exotoxin?

Answer 1

Properties Endotoxin Exotoxin

Chemical nature Lipopolysaccharide protein

Mol Weight 10 kDa 50-1000 kDa

Relationship to cell Part of outer membrane Extracellular

Heat effect Not denatured Denatured

Can be toxoided No Yes

Specificity Low High

Pyrogenicity Yes Occasional

Produced by G-ve bacteria G+ve bacteria

Antigenicity Poor Good

Answer 2

Exotoxins are purposefully released by the bacteria into the surrounding environment.

Endotoxins are lipid components of cell wall of gram negative bacteria, and only get released when the cell lyses (dies).

Both can cause sever illnesses.

Answer 3

Endotoxin are substance released by gram negative bacteria from their lipopolysacharide outer membrane. While endospore are formed by some microbes during unfavoubrale condition like harsh temprature or pressure or low or inadequate supply of food. These endospore are resistant to heat and pH upto great extent and can live in that latent form for thousand of years

Answer 4

An endospore is formed within the bacteria under unfavourable condition and when the bacteria lyses it can only be destroyed in a lab using very high tech equipment. A capsule is a sticky outer layer that is composed of polysaccharide or protein, some protect against dehydration.

Answer 5

EXOTOXINS;these are released by the bacteria into external medium in which they grow.these are nothing but the byproducts of metabolism.these are mainly released by gram +ve bacteria and clostridium species.these are soluble in water also.these are chemically nothing but the high molecular weight,proteins,and engymes.they are thermolabile.toxic to body.

EX;diphtherial toxoid,tetanus toxoid etc.

ENDOTOXINS;these are present in the bacteria and are released only after death and degradation of bacteria.these are chemical constituents or structural units of bacteria.these are mainly released by gram -ve bacteria.these are insoluble in water.these are chemically nothing but the phospholipids,polysaccharides,proteins.they are not thermolabile.not much toxic to body.

EX;vibrio cholera,pasturella pestis,salmonella typhi,bordetella pertusis etc

Answer 6

Exotoxins are toxic substances secreted by bacteria and released outside of the cell. Whereas Endotoxins are bacterial toxins composed of lipids that are within a cell.

Answer 7

exotoxin :

1. exceted by living cell (gram positive bacteria )

2. heat-unstable , 60c , 1 to 2 houres destroy