Here's the all-time list as of the start of the 2008 season:
CAREER
HOMERUNS HR
1 Babe Ruth 659
2 Mickey Mantle 536
3 Lou Gehrig 493
4 Joe DiMaggio 361
5 Yogi Berra 358
6 Bernie Williams 287
7 Graig Nettles 250
8 Don Mattingly 222
9 Jorge Posada 218
10 Dave Winfield 205
11 Roger Maris 203
12 Bill Dickey 202
13 Derek Jeter 195
14 Tino Martinez 192
15 Paul O'Neill 185
16 Charlie Keller 184
17 Tommy Henrich 183
18 Jason Giambi 177
19 Bobby Murcer 175
20 Alex Rodriguez 173
21 Tony Lazzeri 169
22 Joe Pepitone 166
23 Bill Skowron 165
24 Elston Howard 161
25 Roy White 160
26 Hank Bauer 158
27 Joe Gordon 153
28 Bob Meusel 146
29 Reggie Jackson 144
30 Tom Tresh 140
31 Thurman Munson 113
32 Gil McDougald 112
33 George Selkirk 108
34 Mike Pagliarulo 105
35 Hideki Matsui 103
T36 Alfonso Soriano 98
T36 Frankie Crosetti 98
38 Clete Boyer 95
39 Oscar Gamble 87
40 Joe Collins 86
41 Danny Tartabull 81
42 Wally Pipp 80
43 Chris Chambliss 79
44 Rickey Henderson 78
45 Gary Sheffield 76
46 Mike Stanley 72
T47 Matt Nokes 71
T47 Don Baylor 71
T49 Red Rolfe 69
T49 Hector Lopez 69
51 Scott Brosius 65
T52 Kevin Maas 64
T52 Johnny Blanchard 64
T54 Nick Etten 63
T54 Mel Hall 63
T54 Johnny Lindell 63
57 Jesse Barfield 62
58 Ben Chapman 60
T59 Earle Combs 58
T59 Jim Leyritz 58
T61 Roberto Kelly 57
T61 Tony Kubek 57
T61 Lou Piniella 57
64 Gene Woodling 51
T65 Ken Griffey Sr. 49
T65 Chuck Knoblauch 49
T67 Robinson Cano 48
T67 Home Run Baker 48
T67 Willie Randolph 48
T70 Ron Blomberg 47
T70 Andy Carey 47
T72 Jim Spencer 45
T72 Ruben Sierra 45
T72 Aaron Ward 45
T72 Roy Smalley 45
T72 Bill Johnson 45
77 Johnny Mize 44
T78 Shane Spencer 43
T78 Randy Velarde 43
80 Dan Pasqua 42
T81 Darryl Strawberry 41
T81 Steve Balboni 41
T83 Phil Rizzuto 38
T83 David Justice 38
T85 Roger Peckinpaugh 36
T85 Johnny Damon 36
T85 Robin Ventura 36
T88 Mickey Rivers 34
T88 Bobby Richardson 34
90 Bobby Bonds 32
T91 Bud Metheny 31
T91 Rick Cerone 31
T91 Nick Johnson 31
T91 Irv Noren 31
T91 Charlie Hayes 31
T91 Red Ruffing 31
97 Billy Martin 30
T98 Norm Siebern 29
T98 Aaron Robinson 29
T100 Bucky Dent 27
T100 Horace Clarke 27
T100 Snuffy Stirnweiss 27
T100 Jack Clark 27
T100 Butch Wynegar 27
T100 Chad Curtis 27
T100 Raul Mondesi 27
T100 Sammy Byrd 27
T100 Babe Dahlgren 27
T109 Pat Kelly 26
T109 Cecil Fielder 26
T109 Bob Cerv 26
T109 Claudell Washington 26
113 Jake Gibbs 25
T114 Wade Boggs 24
T114 George McQuinn 24
T114 Ben Paschal 24
T114 Eddie Robinson 24
118 Bobby Abreu 23
T119 Cliff Mapes 22
T119 Bobby Brown 22
T119 Jerry Mumphrey 22
T119 Joe Dugan 22
T119 Chili Davis 22
124 Lyn Lary 21
T125 Frank Fernandez 20
T125 Pat Collins 20
T125 Hal Chase 20
T125 Gary Ward 20
T125 Cliff Johnson 20
T130 Steve Sax 19
T130 Joe Sewell 19
T130 Steve Kemp 19
T130 Ron Hassey 19
T130 Mike Gallego 19
T130 Bob Geren 19
T130 Bob Watson 19
T137 Mike Easler 18
T137 Gerald Williams 18
T137 Felipe Alou 18
T137 Tim Raines 18
T137 Steve Whitaker 18
T142 Ken Phelps 17
T142 Russ Derry 17
T142 Ricky Ledee 17
T145 Glenallen Hill 16
T145 John Ellis 16
T145 Enos Slaughter 16
T145 Tony Clark 16
T145 Dixie Walker 16
T145 Jerry Coleman 16
T145 Bill Robinson 16
T145 Ron Kittle 16
T145 Jimmy Williams 16
T145 Wally Schang 16
T145 Ping Bodie 16
T145 Hersh Martin 16
T157 Andy Kosco 15
T157 Melky Cabrera 15
T157 Marv Throneberry 15
T157 Mark Koenig 15
T161 Rondell White 14
T161 Bobby Brown 14
T161 Don Slaught 14
T164 Everett Scott 13
T164 Jake Powell 13
T164 Jim Ray Hart 13
T167 Hensley Meulens 12
T167 Enrique Wilson 12
T167 Gene Michael 12
T167 John Flaherty 12
T167 Elmer Miller 12
T167 Wid Conroy 12
T167 Roger Repoz 12
T167 Dion James 12
T167 Clay Bellinger 12
T176 Andy Phillips 11
T176 Myril Hoag 11
T176 Duffy Lewis 11
T176 Whitey Witt 11
T176 Tommy Byrne 11
T176 Birdie Cree 11
T176 Eric Soderholm 11
T183 Willie Keeler 10
T183 Phil Linz 10
T183 Jack Saltzgaver 10
T183 Danny Cater 10
T183 Harry Wolter 10
T183 Curt Blefary 10
T183 Charley Smith 10
T183 Ray Barker 10
T183 Johnny Callison 10
T183 Del Pratt 10
T183 Ron Woods 10
T194 Ernie Johnson 9
T194 Spud Chandler 9
T194 Ruppert Jones 9
T194 Mariano Duncan 9
T194 John Ganzel 9
T194 Bernie Allen 9
T194 Mike Hegan 9
T194 Bobby Cox 9
T194 Oscar Grimes 9
T194 Jackie Jensen 9
T194 Patsy Dougherty 9
T205 Juan Rivera 8
T205 Joe Lefebvre 8
T205 Roy Hartzell 8
T205 John Mayberry 8
T205 Joel Skinner 8
T205 Jim Mason 8
T205 Bobby Meacham 8
T205 Joe Girardi 8
T205 Don Larsen 8
T205 Elmer Smith 8
T215 Buddy Rosar 7
T215 Fred Hofmann 7
T215 Harry Rice 7
T215 Dusty Cooke 7
T215 Harry Simpson 7
T215 Henry Cotto 7
T215 Alvaro Espinoza 7
T215 Ray Caldwell 7
T215 Harry Bright 7
T215 Dale Long 7
T215 Roy Weatherly 7
T215 Mel Stottlemyre 7
T215 Shelley Duncan 7
T215 Bill Sudakis 7
T215 Jerry Kenney 7
T230 Ron Hansen 6
T230 John Knight 6
T230 Paul Blair 6
T230 Lee Mazzilli 6
T230 Jose Canseco 6
T230 Luke Boone 6
T230 Omar Moreno 6
T230 Miguel Cairo 6
T230 Otto Velez 6
T230 Fred Stanley 6
T230 Luis Polonia 6
T230 Barry Foote 6
T230 Aaron Boone 6
T230 Karim Garcia 6
T230 Jimmie Reese 6
T230 Don Bollweg 6
T230 Fritz Maisel 6
T230 John Vander Wal 6
T230 Mike Blowers 6
T230 Cedric Durst 6
T230 Todd Zeile 6
T230 Luis Sojo 6
T230 Guy Zinn 6
T230 Frank LaPorte 6
T230 Ed Herrmann 6
T255 Carlos May 5
T255 Andre Robertson 5
T255 Tony Fernandez 5
T255 Doug Mientkiewicz 5
T255 Tim Hendryx 5
T255 Danny Hoffman 5
T255 Aurelio Rodriguez 5
T255 Steve Souchock 5
T255 Truck Hannah 5
T255 Deion Sanders 5
T255 Billy Bryan 5
T255 Tuck Stainback 5
T255 Herm McFarland 5
T255 Rocky Colavito 5
T255 Oscar Azocar 5
T255 Mark Whiten 5
T255 Rusty Torres 5
T255 Walt Williams 5
T255 Bert Daniels 5
T255 Lu Clinton 5
T255 Buddy Hassett 5
T276 Kent Hadley 4
T276 Jack Chesbro 4
T276 Elliott Maddox 4
T276 Rollie Hemsley 4
T276 Bob Seeds 4
T276 Ed Lopat 4
T276 Jesse Hill 4
T276 Harvey Hendrick 4
T276 Daryl Boston 4
T276 John Olerud 4
T276 Elrod Hendricks 4
T276 Brian Dayett 4
T276 Wilson Betemit 4
T276 Juan Beniquez 4
T276 Ron Swoboda 4
T276 Rafael Santana 4
T276 Bubba Crosby 4
T276 Ray Demmitt 4
T276 Art Jorgens 4
T276 Tom Brookens 4
T276 Harry Niles 4
T276 Aaron Guiel 4
T276 Don Savage 4
T276 Jim Lyttle 4
T276 Pat Sheridan 4
T276 Jerry Narron 4
T276 Sandy Alomar Sr. 4
T276 Ed Levy 4
T276 Craig Wilson 4
T276 Kid Elberfeld 4
T276 Dave Kingman 4
T276 Jack Quinn 4
T308 Bill Bevens 3
T308 Frank Colman 3
T308 Chick Fewster 3
T308 Dave Silvestri 3
T308 Clyde Engle 3
T308 John Anderson 3
T308 Jerry Lumpe 3
T308 Gary Roenicke 3
T308 Dale Berra 3
T308 Hugh High 3
T308 Jimmy Austin 3
T308 Jay Buhner 3
T308 Mark Salas 3
T308 Herb Pennock 3
T308 Otis Johnson 3
T308 Al Orth 3
T308 Jerry Priddy 3
T308 Bob Shawkey 3
T308 Tom Morgan 3
T308 Joe Bush 3
T308 Andy Fox 3
T308 Johnny Sturm 3
T308 Luis Aguayo 3
T308 Lee Magee 3
T308 Jeff Sweeney 3
T308 Paddy Baumann 3
T308 George Zeber 3
T308 Kenny Lofton 3
T308 Jimmie Hall 3
T308 Dennis Werth 3
T308 Whitey Ford 3
T308 Billy Hunter 3
T308 Gary Thomasson 3
T308 Doc Cook 3
T308 Ryan Thompson 3
T308 Rick Dempsey 3
T308 Carl Mays 3
T308 Mike Aldrete 3
T308 Ron Coomer 3
T308 Johnny Hopp 3
T308 Dave Collins 3
T349 Bob Tillman 2
T349 Joe Gallagher 2
T349 Bob Turley 2
T349 Andy Stankiewicz 2
T349 George Pipgras 2
T349 Les Nunamaker 2
T349 Wayne Tolleson 2
T349 Joe Page 2
T349 Dave Fultz 2
T349 Matt Lawton 2
T349 Ray Fisher 2
T349 Hank Johnson 2
T349 Roy Cullenbine 2
T349 Frank Delahanty 2
T349 Braggo Roth 2
T349 Frank Gilhooley 2
T349 Harry Williams 2
T349 Mike Garbark 2
T349 Sad Sam Jones 2
T349 Jake Stahl 2
T349 Phil Lombardi 2
T349 Chicken Hawks 2
T349 Jay Johnstone 2
T349 Red Kleinow 2
T349 Russ Davis 2
T349 Josh Phelps 2
T349 Nick Green 2
T349 Fred Talbot 2
T349 Champ Osteen 2
T349 Loren Babe 2
T349 Al Downing 2
T349 Jack Phillips 2
T349 Jack Lelivelt 2
T349 Matty Alou 2
T349 Ham Hyatt 2
T349 Alex Johnson 2
T349 Bob Grim 2
T349 Bob Brower 2
T349 Sammy Vick 2
T349 Bill Knickerbocker 2
T349 Dave Revering 2
T349 Fritz Peterson 2
T349 Spike Owen 2
T349 Johnny Allen 2
T349 Ken Sears 2
T349 Tom Shopay 2
T349 Bill Renna 2
T349 Willie Miranda 2
T349 Lenn Sakata 2
T349 Rube Oldring 2
T349 Eddie Phillips 2
T349 Ruben Rivera 2
T401 Celerino Sanchez 1
T401 Steve O'Neill 1
T401 Roy Johnson 1
T401 Charlie Silvera 1
T401 Gus Triandos 1
T401 Fritz Brickell 1
T401 Dutch Ruether 1
T401 Jack Powell 1
T401 Jesse Tannehill 1
T401 Allie Clark 1
T401 Monk Dubiel 1
T401 Mark Bellhorn 1
T401 Michael Coleman 1
T401 Larry Milbourne 1
T401 Jesse Gonder 1
T401 Juan Espino 1
T401 Earle Gardner 1
T401 Sherm Lollar 1
T401 Vito Tamulis 1
T401 Ernie Courtney 1
T401 Billy Cowan 1
T401 Brad Gulden 1
T401 Billy Gardner 1
T401 Juan Bonilla 1
T401 Ross Moschitto 1
T401 Leo Hernandez 1
T401 Ken Silvestri 1
T401 Jose Cruz 1
T401 Erick Almonte 1
T401 Joe Lake 1
T401 Fred Heimach 1
T401 Al Shealy 1
T401 Dutch Sterrett 1
T401 Dick Kryhoski 1
T401 Atley Donald 1
T401 John Kennedy 1
T401 Bob Hale 1
T401 Jim Delsing 1
T401 Claud Derrick 1
T401 Jimmy Walsh 1
T401 Lindy McDaniel 1
T401 Mike Patterson 1
T401 Fernando Gonzalez 1
T401 Pee Wee Wanninger 1
T401 Doc Edwards 1
T401 Johnny Oates 1
T401 Sal Maglie 1
T401 Darrell Johnson 1
T401 Andy Cannizaro 1
T401 Howard Shanks 1
T401 Vic Raschi 1
T401 Wendell Alston 1
T401 Julie Wera 1
T401 Brian Doyle 1
T401 Buster Mills 1
T401 Homer Bush 1
T401 Russ Ford 1
T401 Bob Melvin 1
T401 Kevin Thompson 1
T401 Kelly Stinnett 1
T401 Mickey McDermott 1
T401 Johnny Sain 1
T401 Sal Fasano 1
T401 Danny Walton 1
T401 Art Ditmar 1
T401 Marcus Thames 1
T401 Bob Schmidt 1
T401 Wilson Delgado 1
T401 Rich McKinney 1
T401 Ray Morehart 1
T401 Clark Griffith 1
T401 Bill Hogg 1
T401 Monte Pearson 1
T401 Jack Reed 1
T401 Bobby Ramos 1
T401 Johnny Grabowski 1
T401 Walt Alexander 1
T401 Ruben Amaro 1
T401 Joe Glenn 1
T401 Mickey Klutts 1
T401 Allie Reynolds 1
T401 Victor Mata 1
T401 Tom Hughes 1
T401 Todd Greene 1
T401 Russ Van Atta 1
T401 Del Paddock 1
T401 Rey Sanchez 1
T401 Joe Oliver 1
T401 Walter Blair 1
T401 Steve Sundra 1
T401 Felix Jose 1
T401 Charlie Hemphill 1
T401 Rick Bladt 1
T401 Harry Howell 1
T401 Pete Ward 1
T401 Ray Scarborough 1
T401 George Murray 1
T401 Matt Howard 1
T401 Spec Shea 1
T401 Mike Humphreys 1
T401 Ira Thomas 1
T401 Rich Coggins 1
T401 Chris Turner 1
T401 Eli Grba 1
T401 Wilcy Moore 1
T401 Duke Sims 1
T401 Archie Moore 1
T401 Curtis Pride 1
T401 Muddy Ruel 1
T401 Gene Robertson 1
T401 Billy Sample 1
T401 Mike McNally 1
T401 George Scott 1
T401 David Dellucci 1
T401 Tom Zachary 1
T401 Jose Molina 1
T401 Jimmy Wynn 1
T401 Toby Harrah 1
T401 John Miller 1
Joe DiMaggio hit 361 home runs during his 13 year career, all with the New York Yankees.
The MLB home run record is held by Barry Bonds with 762 home runs.
You need to be more specific. Babe Ruth hit many record breaking home runs.
475 by Willie Stargell.
Barry Bonds holds the record for career home runs with 762 and the mark for most homers in a season with 73.
In 1927, Babe Ruth hit a record 60 home runs for the Yankees. This record stood until Roger Maris hit 61 home runs in 1961, also playing for the Yankees.
Derek Jeter hit 260 career home runs with the New York Yankees from 1996 to 2014.
Mickey Mantle of the New York Yankees with 18.
Joe DiMaggio hit 361 home runs during his 13 year career, all with the New York Yankees.
Steve Balboni. Balboni played 295 games for the Yankees from 1981-1983 and hit 36 home runs for the Royals in 1985 which is still the Royals all time season record.
Slugger Barry Bonds holds the record for the most home runs in a career. In the course of his career, he blasted 762 out of the park.
"The Iron Horse" hit 493 home runs during his career with the New York Yankees.
Derek Jeter hit 260 career home runs with the New York Yankees from 1995 to 2014.
Ted Williams holds the record for most career home runs by a Boston Red Sox player with 521.
Bernie Williams 22 Postseason Home RunsAs of 2009, Bernie Williams has the most career postseason home runs as a new York Yankee with 22. Williams is second all time in Major League Baseball behind Manny Ramirez who holds the record for most career postseason home runs with 29. Mickey Mantle holds the all time record for most World Series home runs with 18.
Babe Ruth hit 714 career home runs of which 659 were hit with the New York Yankees.
The MLB home run record is held by Barry Bonds with 762 home runs.