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Ineffective Erythropoiesis as described by Goljan's Rapid Review in Pathology:

RBC's with alpha-chain inclusions undergo apoptosis in the bone marrow. You can see why the term is as such because RBCs are damaged/apoptosed/removed prior to release, resulting in 'ineffective' erythropoiesis.

Ineffective erythropoiesis is the active erythropoiesis with premature death of created red blood cells RBCs, a decreased output of red blood cells from the bone marrow and consequently anemia.

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Q: What is ineffective erythropoiesis?
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