The substance tricks the neuron into releasing a flood of dopamine back in the synaptic cleft The substance tricks the neuron into releasing a flood of dopamine back in the synaptic cleft
Cocaine is an agonist to the dopamine receptor. Because it is an agonist, cocaine sits on the dopamine receptor, thus inducing dopamine chemicals to flood into the brain and body. Dopamine makes a person feel euphoria......
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neurons; dopamine
neurons; dopamine
Using drugs causes an abnormal release of neurotransmitters in the brain, which can disrupt the normal communication between brain cells. Over time, this can lead to changes in the brain's structure and function, often resulting in decreased natural production of neurotransmitters.
The could be a stress / trauma related impairment of the dopamine system that results in a reduced capacity to experience pleasure and correlates with addiction. The dopamine recepters are unable or reduced in their ability to reuptake dopamine and thus a flood of dopamine becomes necessary in order to feel any level of pleasue. That's my best guess. Come see me at sonoranhealingcenter.com
that's how the mafia works
PCP is more addictive than LSD because it works on Dopamine Receptors in the reward pathway. Normally, inhibitory neurotransmitters are active in the synapse. These neurotransmitters inhibit dopamine from being released. When endorphins activate the dopamine receptors, the release of inhibitory neurotransmitters is shut down. Without inhibition, dopamine can be released. PCP mimics endorphins and binds to opiate receptors, turning off dopamine inhibition. Dopamine is allowed to flood the synapse, producing immediate feelings of sedation and well-being. 10 bucks says your in Med Chem with Mr. Choi.
Dopamine is produced by nerve cells in the brain. There is no dopamine gland.
Dopamine is the neurotransmitter that is lacked in Parkinson's Disease.
a dopamine chaser is one who chases or craves life experiences that trigger excitement, resulting in a dopamine high.