Mutations in the iduronate-2-sulphatase (IDS) gene cause both forms of MPS II (mild and severe). Nearly all individuals with Hunter syndrome are male, because the gene that causes the condition is located on the X chromosome.
Hurler (MPS I H), Hurler-Scheie (MPS I H/S), Scheie (MPS I S), Hunter (MPS II), Sanfilippo (MPS III), Morquio (MPS IV), Maroteaux-Lamy (MPS VI),
Each type of MPS is caused by a deficiency of one of the enzymes involved in breaking down GAGs.
MPS IV B is considered the milder form of the condition. The enzyme, beta-galactosidase, is deficient in MPS IV B. The gene involved with MPS IV B (GLB1) is located on chromosome 3.
Mutations in the alpha-L-iduronidase (IDUA) gene located on chromosome 4 cause the MPS I disorders (Hurler, Hurler-Scheie, and Scheie syndromes
Common problems include abnormal heart valves, narrowing of the blood vessels in the heart, and weak heart muscles (cardiomyopathy). Patients with MPS I H and the severe form of MPS II usually have damage to the mitral valve
MPS I, MPS III, MPS IV, MPS VI, MPS VII, and MPS IX are inherited in an autosomal recessive manner which means that affected individuals have two altered or non-functioning genes,
528In total there are 646 Members of Parliament (MPs) in the UK Parliament. Excluding the 59 Scottish MPs, 18 Northern Irish MPs and 41 Welsh MPs, there are 528 English MPs.
No. Only MPs from Scotland are Scottish MPs. There are MPs in Westminster from Scotland, England, Wales and Northern Ireland. There are also MSPs, which are Members of the Scottish Parliament. They are different to the Scottish MPs. MPs attend Westminster in London. MSPs attend the Scottish Parliament in Edinburgh.
MPS Finance was created in 2001.
MPS Group was created in 1992.
mps/mpc=1
Opinions among MPs on homework vary. Some believe it is necessary for reinforcing learning and developing important study skills, while others argue that it can be detrimental to students' well-being and stress levels. Ultimately, the stance on homework depends on individual beliefs and experiences.