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There are voltage-gated ion channels and ligand-gated ion channels, and since both are stimuli the term stimulus-gated is a redundancy.
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Ionotropic receptors are ligand-gated or transmitter gated ion channels. The binding of a neurotransmitter or other ligand to a particular site on a domain of a protein in the receptor causes a conformational change in the protein subunits. This allows a certain ion to pass through, poteitally potassium, sodium or chloride. There are two types of ionotropic receptors, non-NMDA and NMDA. Both are ligand gated receptors, however the NMDA is also voltage gated.
It is a channel through a membrane that can be opened or closed by chemical or electrical events.
Change in the voltage across the membrane, ligand binding, and mechanical stress.
april 25th 1994
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bob marley.