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Isopropyl is in alcohol. which makes it dissolve. also alcohol dissolves both polar and non-polar substances , and permanent marker is non-polar. which means that it share electrons equally.

I hope this helped ;)

Further explaination:

isopropanol/Ispropyl (or called rubbing alcohol) is a solvent that has polar molecules (molecules with a positive charged molecule that sticks to a negative charged molecule).

If you sniff a sharpie, it has a sharp, alcohol smell, right? Sharpies have n-propanol alcohol, n-butanol, and diacetone alcohol in them. They have pretty similar structures to rubbing alcohol. Most alcohol molecules contain hydrogen, oxygen, and carbon. All alcohol have polar molecules.

There is a "like dissolve like" rule. This means Polar solvent+Polar solvent=dissolve/removal. OR non-polar solvent+nonpolar solvent=dissolve/removal.

The closer the types of molecule and chemical make-ups are, the more likely they are to dissolve or be removed.

http://www.middleschoolchemistry.com/multimedia/chapter5/lesson7

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Q: WHY does alcohol remove permanent marker?
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