0
due to lack of b12
No HCl and intrinsic factor = pernicious anemia
Wiki User
∙ 12y ago
Add your answer:
Earn +20 pts
Aids in absorption of vitamin b12?
It is called intrinsic factor, which enables the absorption of B12. Intrinsic factor is found in the parietal cells (mucosa cells) of the stomach lining.
What role of the stomach is essential to life?
production of intrinsic factor
Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?
Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.
What is the rate and extent to which a vitamin is absorbed and used in the body is known as?
intrinsic factor
Which pathway of blood coagulation has factor VIII th as important factor?
Intrinsic pathway of coagulation (measured as PTT in laboratories).
Aids in absorption of vitamin b12?
It is called intrinsic factor, which enables the absorption of B12. Intrinsic factor is found in the parietal cells (mucosa cells) of the stomach lining.
What the importance of intrinsic factor?
Intrinsic factor is glycoprotein that is produced by the parietal cells of the stomach.
Why do you need intrinsic factor?
Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.
Which cells produce intrinsic factor?
Intrinsic factor is produced in the fundus and body of the stomach by parietal cells that line the stomach. The purpose of intrinsic factor is so vitamin B can be absorbed in the small intestine.
Which blood component is associated with Von Willenbrand disease?
von Willebrand disease results from inadequate von Willebrand factor. This problem is a blood clotting disorder.
What problems are associated with an inadequate diet?
many
What foods increase intrinsic factor?
what foods help increase intrisic factor
Which nutrient requires intrinsic factor for absorption?
b12
Where does the absorption of vitamin B12 occur?
The vitamin B12 is a very important nutrient; it lowers risk of stroke, heart disease, cancer, Parkinson's, and Alzheimer's disease. The vitamin begins to absorb in the mouth, in contrast to most nutrients.
What is the function of the intrinsic factor?
Intrinsic factor is necessary for the proper absorption of vitamin b12 which is necessary for red blood cell maturation, and therefore prevents pernicious anemia
How does one increase production of intrinsic factor?
what foods help increase intrisic factor
Is hydrochloric acid necessary to produce the intrinsic factor for cobalamin?
No, hydrochloric acid (HCl) is not necessary to produce the intrinsic factor for cobalamin. HCl is needed along with gastric enzymes to free Cobalamin (B12) from its polypeptide linkages in food. The intrinsic factor involved with the digestion and absorption of Cobalamin (B12) is a glycoprotein.
