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10 million Americans have a positive ANA. About 1.5 million Americans have lupus. Of the 1.5 million who have lupus 95-98% have a negative ANA. People are more likely to have a positive ANA as they age. Many people with a positive ANA never show any signs of autoimmune disease at all. A speckled titer can be indicative of lupus. No one can predict or even give odds about your chance of defeloping lupus.

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Q: If you have RA with a speckled ANA titer 160 does this mean you will eventually develop Lupus?
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Do you fast for lupus titer?

Unless your doctor tells you otherwise, fasting is generally not necessary for lupus antibody testing.


Does everyone with a positive ANA test have lupus?

No. Approximately 10 million Americans have a positive ANA. There are about 1.5 million Americans with lupus. 95-98% of people with lupus have a positive ANA, the others do not. Most people with lupus have a positive ANA, but some do not. Many people have a positive ANA and have another autoimmune disease or no disease at all. The immunofluorescent pattern of the ANA is more significant than the titer number. Lupus usually presents with a speckled rather than homogeneous pattern. There are no definitive biomarkers for lupus.


ANA titer reading for 1.320?

The ANA titer is the number of times the blood sample has to be diluted before a sample remains that has no antinuclear antibodies. The first dilution is 1:40, then 1:80, then 1:160, then 1:320. The ANA number does not correlate to the level of disease activity. Many people have a positive ANA and no disease at all. In lupus, the immunofluorscent pattern is of more significance than the titer. A speckeld pattern points to the likelihood of lupus.


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An positive ANA (antinuclear antibody) means that you make antibodies that attack the circulating debris of the nucleii of your own cells that have died. A titer of 320 means that your blood had to be diluted320 times before they got a sample that had no antinuclear antibody. Typically the numbers are 40, 80, 160, 320, 640, and so on. Lupus presents a speckled pattern, not a nucleolar pattern. 10 million Americans have a positive ANA. Only 1.5 million have lupus. Many people have a positive ANA and no active disease of any kind. Unless you are having some kind of symptoms, don't be overly concerned.


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What does ana screen ifa positive?

ANA means anti-nuclear antibodies. There are antibodies that a person might make against the nuclear material of their own cells that have died, broken down and are circulating in the blood stream. 10 million Americans have a positive ANA. Many have no disease. The older one is, the more likely one is to have a positive ANA. The ANA test is a titer which means the number represents how many times the lab had to dilute the blood to come up with a sample with no autoantibodies. IFA refers to immunofluorescence. People with lupus who have a positive ANA are likely to have a speckled pattern under immunofluorescence.