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Since people with the sickle cell allele trait are resistent to malaria, if malaria were eliminated there would be no change in the frequncy of sickle cell allele. This is because the presense of malaria does not have an affect on patients with the sickle cell allele trait.

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11y ago
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6y ago

The sickle cell allele frequency will increase if malaria is a significant selection pressure acting on that population, until the fatalities from sickle cell anemia begin to balance the survivors of malaria.

The sickle cell allele frequency will be unaffected or even decline if malaria is not a significant selection pressure acting on that population.

It all depends on the rate of malaria infection in the population!

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Q: If malaria were eliminated how might the frequency of the sickle-cell allele change over time?
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