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How many time greater is the affinity of hemoglobin for carbon monoxide greater than the affinity of hemoglobin for oxygen?
Wiki User
∙ 14y ago
The affinity of hemoglobin for CO is roughly 20,000 times greater than that of oxygen in vitro.
In vivo, the affinity of hemoglobin for CO is roughly 200-225 greater than that of oxygen.
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O2 has stronger bond than CO. Therefore, the oxygen in CO loves the iron in the hemoglobin as iron ends with two electrons which complete the 6 electrons in the oxygen. In vivo, the affinity of hemglobin for CO is about 153 from 141x153/141.
by amin elsersawi
Wiki User
∙ 14y ago
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Carbon monoxide is a deadly odorless and colorless gas?
Yes, and it has an affinity for hemoglobin 400 times greater than oxygen.
In an unventilated space carbon monoxide from smoke or car exhaust builds up in the blood combining with hemoglobin to form?
When CO is not ventilated it binds to hemoglobin, which is the principal oxygen-carrying compound in blood; this produces a compound known as carboxyhemoglobin. The traditional belief is that carbon monoxide toxicity arises from the formation of carboxyhemoglobin, which decreases the oxygen-carrying capacity of the blood and inhibits the transport, delivery, and utilization of oxygen by the body. The affinity between hemoglobin and carbon monoxide is approximately 230 times stronger than the affinity between hemoglobin and oxygen so hemoglobin binds to carbon monoxide in preference to oxygen. ~ Wikipedia.
What is more dangerous CO or CO2?
Carbon monoxide binds very strongly to the iron atoms in hemoglobin, the principal oxygen-carrying compound in blood. The affinity between CO and hemoglobin is 200 times stronger than the affinity between hemoglobin and oxygen. When CO binds to the hemoglobin it cannot be released nearly as readily as oxygen would be. The preferential binding of carbon monoxide to heme iron is the main reason for carbon
How does carbon monoxide affect oxygen saturation?
The problem with carbon monoxide is that haemoglobin would much rather take it up than oxygen. In fact, haemoglobin has a 500 times greater affinity for carbon monoxide than with oxygen. Without oxygen being transported to our cells, respiration ceases and basic metabolic reactions in our body stop, and we quickly die from carbon monoxide poisoning.
Does carbon monoxide bind to hemoglobin or oxygen better?
Carbon monoxide bind easily to hemoglobin.
What is Hemoglobin's affinity to ethane butane and propane?
I'd expect this to be negligible. The molecules which do bind to haemoglobin are oxygen, carbon monoxide and nitric oxide.
What is the complex that forms when carbon monoxide and hemoglobin combine?
Carboxyhemoglobin is the complex fomed by the combination of carbon monoxide and hemoglobin.
Where is hemoglobin found in your body?
Hemoglobin is found in the red blood cells.
How does CO affect the body?
Carbon Monoxide is a very lethal substance that disrupts many biological activities in the body. For one, it has a greater affinity for hemoglobin than oxygen. Exposure to carbon monoxide reduces the amount of oxygen that is transported by erythrocytes to the tissues in the body. Carbon monoxide also binds to the binuclear center of cytochrome c oxidase, thus hindering the flow of electrons in the electron transport chain.
Why is carbon monoxide posionous but carbon dioxide is not?
Yes carbon monoxide is harmful. It is reacting with hemoglobin.
Does carbon monoxide bond to hemoglobin more effectively then oxygen does?
Yes - haemoglobin has a higher affinity for carbon monoxide than oxygen. This means that it will bind to carbon monoxide in preference.The binding of carbon monoxide at one site of the haemoglobin increases the affinity for oxygen at the other 3 sites - which may cause problems as the oxygen is not released when it should be.Yes, irreversible while with oxygen reversibleYes, that's why you suffocate if you get stuck in a car with the exhaust coming in. The Carbon Monoxide sticks to your haemoglobin so the oxygen cannot.
Why nitrogen in air does not react with hemoglobin as it is present in greater percentage then oxygen?
Nitrogen gas is nearly an inert gas. Hemoglobin is optimized for bonding with oxygen, but bonds even better to carbon monoxide (which makes carbon monoxide such an effective poison).
