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Thalidomide leads to the forming of deformed and flipper like limbs in babies.

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Q: How did thalidomide affect babies?
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Why was thalidomide prescribed to a pregnant women?

Doctors often prescribed Thalidomide to pregnant women to treat morning sickness and as a sedative to assist with sleep. Thalidomide was sold from 1957 until 1961. The product was withdrawn when it was discovered that Thalidomide was teratogenic - causing malformations of an embryo or foetus. Countless babies were born with birth-defects; most notably missing limbs.


Why was the testing inappropriate for thalidomide?

It Caused Unexpected Damage To The Babies Of Thousands Of Pregnant Women.


Who invented thalidomide?

Dr.R.Kunz and Dr.H.Keller invented thalidomide in Germany


How did Thalidomide help pregnant women?

Thalidomide was supposed to be an effective sedative for pregnant women, but thalidomide caused birth defects and peripheral neuropathy.


What is the influence of Rh factor on babies?

Do you mean how can they affect babies or how can they affect the baby's blood type?


How did thalidomide cause birth deformities?

This occurred due to the fact that the first manufacturer of thalidomide was a German pharmaceutical company - which first sold this drug in October of 1957. This was followed by British approval of the drug. Subsequently, over the next ten years or so, about 2,500 "thalidomide babies" were born in Germany, and about 2,000 in Great Britain. The birth defect is called phocomelia, a shortening of the limbs, in which they appear to look like the flippers on a seal. Also, the FDA did not approve thalidomide in the U.S. (although quite a few tablets found their way to the U.S., despite the FDA ban).


What are some books about the thalidomide disaster?

Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine by Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicineby Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom


What was Thalidomide originally intended to cure?

Thalidomide was orginally created to help cure morning sickness (a common side effect of pregnancy) and it worked out great! but the side effect was that it made gross defects on the babies born(missing/distorted limbs, etc.) so it was take off the shelves in 1962 and is not used for this purpose anymore.


How does the drug thalidomide work?

Thalidomide regulates the immune response by suppressing a protein, tumor necrosis factor alpha.


When in pregnancy did thalidomide affect baby?

The thalidomide sensitive period goes from day 21 past conception onwards to day 42. (Dr Janet McCredie, "Thalidomide - Birth Defects Explained", London, The Royal Society of Medicine Press, 2007, p. 189 and many other places in the book} McCredie suggests, p. 126, that the hypothesis of neural crest injury is the underlying pathogenetic mechanism of many congenital malformations. And concludes, pp. 150 - 151, that the thalidomide-sensitive period coincides with neural crest development, but not with limb development That's what I understand. I have no knowledge of (human) biology and related sciences. I'm only a dumb thalidomide-monster.


What is the chemical formula of thalidomide?

C13H10N2O4


What actors and actresses appeared in Happy Birthday Thalidomide - 2004?

The cast of Happy Birthday Thalidomide - 2004 includes: Mat Fraser