Thalidomide leads to the forming of deformed and flipper like limbs in babies.
approx. 10,000
Do you mean how can they affect babies or how can they affect the baby's blood type?
Have an otopsie and see what their cause of death was and what was in their system.
The Thalidomide tragedy was caused in part by a lack of knowledge of stereochemistry. One of the stereoisomers was toxic the other was not.
Age does affect the exposure to chemicals. Babies and children generally have a higher risk of negative effects due to the exposure of harmful chemicals. An unborn fetus is the most susceptible. This is due to the fact that their organs are not fully developed.
i think it is something to do with cells?NOPE, its all about genes.People mate with others from another population introducing their genes into the population.
Doctors often prescribed Thalidomide to pregnant women to treat morning sickness and as a sedative to assist with sleep. Thalidomide was sold from 1957 until 1961. The product was withdrawn when it was discovered that Thalidomide was teratogenic - causing malformations of an embryo or foetus. Countless babies were born with birth-defects; most notably missing limbs.
It Caused Unexpected Damage To The Babies Of Thousands Of Pregnant Women.
Dr.R.Kunz and Dr.H.Keller invented thalidomide in Germany
Thalidomide was supposed to be an effective sedative for pregnant women, but thalidomide caused birth defects and peripheral neuropathy.
Do you mean how can they affect babies or how can they affect the baby's blood type?
This occurred due to the fact that the first manufacturer of thalidomide was a German pharmaceutical company - which first sold this drug in October of 1957. This was followed by British approval of the drug. Subsequently, over the next ten years or so, about 2,500 "thalidomide babies" were born in Germany, and about 2,000 in Great Britain. The birth defect is called phocomelia, a shortening of the limbs, in which they appear to look like the flippers on a seal. Also, the FDA did not approve thalidomide in the U.S. (although quite a few tablets found their way to the U.S., despite the FDA ban).
Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine by Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicineby Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom
Thalidomide was orginally created to help cure morning sickness (a common side effect of pregnancy) and it worked out great! but the side effect was that it made gross defects on the babies born(missing/distorted limbs, etc.) so it was take off the shelves in 1962 and is not used for this purpose anymore.
Thalidomide regulates the immune response by suppressing a protein, tumor necrosis factor alpha.
The thalidomide sensitive period goes from day 21 past conception onwards to day 42. (Dr Janet McCredie, "Thalidomide - Birth Defects Explained", London, The Royal Society of Medicine Press, 2007, p. 189 and many other places in the book} McCredie suggests, p. 126, that the hypothesis of neural crest injury is the underlying pathogenetic mechanism of many congenital malformations. And concludes, pp. 150 - 151, that the thalidomide-sensitive period coincides with neural crest development, but not with limb development That's what I understand. I have no knowledge of (human) biology and related sciences. I'm only a dumb thalidomide-monster.
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The cast of Happy Birthday Thalidomide - 2004 includes: Mat Fraser