Does Tylenol effect platelets

Answer 1

Traditionally, the medication Acetaminophen (Tylenol is one brand name of the drug) has been considered not to influence platelet function in the human body. However, there is a growing body of small-sample research efforts (involving a quite small number of subjects) that show a clear dose-dependent interaction between Acetaminophen and platelet aggregation for at least 90 minutes after a dose. This is not widely seen as an indication that Acetaminophen use is a problem, but it does indicate the wisdom of starting some large-scale studies. At this time, a major concern regarding Acetaminophen and platelet function is that Acetaminophen not be used while taking Coumadin or other Warfarin medications. The two drugs interact to dramatically depress platelet function which can lead to severe internal bleeding. Other major Acetaminophen concerns are that dose instructions be followed precisely, and that the medication not be used for more than 10 days without a physician's supervision.Acetaminophen is a tricky drug -- it is a safe short-term analgesic when used at exactly the correct dosage, but it doesn't require a large overdose to cause serious or even fatal damage to the liver and kidneys.