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Point mutations

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Q: Changes in a DNA sequence caused by substitution of one nucleotide for another?
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What is a point mutuation?

A point mutation is a type of genetic mutation that involves a change in a single nucleotide base pair in DNA. This can result in the substitution of one nucleotide for another, the insertion of an extra nucleotide, or the deletion of a nucleotide. Point mutations can lead to changes in the amino acid sequence of a protein, which can affect its structure and function.


Which mutation occurs when one nucleotide is replaced with another base?

Substitution


If one nucleotide is replaced by another it is called?

frameshift mutation


What is a nucleotide substitution error?

Before you know what a nucleotide substitution error is, you have to know what a nucleotide is. A nucleotide holds the DNA strand together and helps make copies. When a Strand is ready to be copied, Let's say one nucleotide reads for G(Guanine), then another nucleotide would be added, which would mean C (Cytosine) would be added. A substitution error would mean that, that instead of Cytosine being added, Thymine, Adenine, Uracil, or Guanine could be added, resulting in a mutation.


True or false The substitution of one nucleotide for another in the gene never affects the function of the protein?

true


Which mutation occurs when one nucleotide base in replaced with another base?

the substitution has little effect because UGU and UGC both translate into the same amino acid--cysteine.


How are substitution mutations caused?

A substitution mutation in genetics is where one of the nucleotide bases of DNA is swapped for another. These mutations may or may not affect the protein that is being coded.


What is point mutation substitution?

When a nitrogen base is substituted for a different one so it may code for a different amino acid. Sometimes substitution still codes for a same amino acid, in which case it becomes a silent mutation, but in other times it may alter the protein entirely.


What are types of point mutation?

The types of point mutations are: base-pair substitution, insertions, deletions, and frameshift mutations. In base-pair substitution, one nucleotide and its corresponding partner are replaced with another pair of nucleotide. In insertion, nucleotide pairs are added to a gene. In deletion, nucleotide pairs are taken out of a gene. Frameshift mutation happens as a result of insertion or deletion when more or less than three (or a multiple of three) nucleotide pairs are added to or taken from a gene.


What is a change in nucleotide-base sequence of a gene or DNA molecule?

A change in a nucleotide base sequence is known as a point mutation, this is when one of the bases(A,T,C,G) is swapped with another. This causes for the amino acid to change, which can change the function of the amino acid chain.


Why do chromosome mutations occur most often during nuclear divisions?

Chromosome mutations occur during nuclear division because when the sequence of nucleotides are being placed substitutions, and frameshifts can occur, causing mutations. Substitution is when one nucleotide replaces another and frameshift mutation is when a nucleotide deletes, causing codons to be incorrectly read.


How do transciption and translation change information from one form to another?

From nucleic acids to amino acids. Transcription copies the nucleotide sequence of DNA into RNA; in translation ribosomes recreate the messenger-RNA pattern into a copy of the sequence.