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These two medications do not have a pharmacological interaction according to the literature. However, phentermine in higher and/or chronic doses can cause mood changes, and so can prednizone. Be certain to discuss this with your caregiver, so you know what to expect. If you don't expect mood changes and they occur, it can be pretty.... surprising.

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15y ago
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Wiki User

9y ago

Taking Medrol while taking phentermine isn't recommended. The reason for that is that phentermine decreases the effectiveness of the Medrol.

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Wiki User

6y ago

Yes. There doesn't seem to be any interaction between the two.

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Wiki User

11y ago

yes

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Anonymous

Lvl 1
4y ago

Can you take methylpredolone with phentermine

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Q: Can you take methylprednisolone with phentermine?
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